Flight Physiology Basics

040-02-01Pablo Asensio Martínez2026-04-011 min

The Atmosphere

Standard Atmosphere (ISA) assumes:

  • Pressure: 1013.25 hPa at MSL, decreasing with altitude.
  • Temperature: +15°C at MSL, decreasing by 2°C/1000 ft (1.98°C) up to the Tropopause (36,090 ft).
  • Composition: 78% Nitrogen, 21% Oxygen, 1% other gases. (Constant up to ~70,000 ft).

Gas Laws

  • Boyle's Law ($P_1 V_1 = P_2 V_2$): Pressure and volume are inversely proportional.
    • Relevance: Trapped gases expand on ascent (ears, sinuses, teeth, stomach, intestine).
  • Dalton's Law ($P_{Total} = P_1 + P_2 + ...$): Total pressure is the sum of partial pressures.
    • Relevance: As altitude increases, total pressure drops, so the partial pressure of oxygen ($ppO_2$) drops, leading to Hypoxia.
  • Henry's Law: The amount of gas dissolved in a liquid is proportional to its partial pressure.
    • Relevance: Decompression Sickness (DCS). Nitrogen bubbles form in blood when pressure drops rapidly (Scuba diving + Flying).

Hypoxia

Students in hypobaric chamber simulating hypoxia

A state of oxygen deficiency in the body.

  1. Hypoxic Hypoxia: Insufficient oxygen in the air (Altitude).
  2. Anemic Hypoxia: Blood cannot carry oxygen (CO Poisoning, Smoking reduces hemoglobin efficiency).
  3. Stagnant Hypoxia: Blood not moving (G-forces, Heart failure, Cold).
  4. Histotoxic Hypoxia: Cells cannot use oxygen (Alcohol, Cyanide).

Symptoms: Euphoria, cyanosis (blue lips/fingernails), impaired judgment, tunnel vision. Time of Useful Consciousness (TUC): Decreases rapidly with altitude (e.g., FL300: 1-2 mins; FL400: 15-20 secs).

Hyperventilation

Over-breathing usually caused by stress/anxiety.

  • Effect: Flushes too much CO2 from the blood (Hypocapnia). Blood becomes alkaline.
  • Symptoms: Dizziness, tingling in hands/feet, visual tunneling (similar to hypoxia).
  • Action: Slow breathing rate.
Written and reviewed by

Pablo Asensio

Aeronautical engineer. Passed the thirteen EASA ATPL(A) theoretical knowledge exams studying from these very notes. Writes and reviews each topic against the Part-FCL Learning Objectives.